Comprehensive Cardiovascular Screening

Comprehensive Cardiovascular Screening

We provide a state of the art cardiovascular screening test that analyzes blood for lipid markers and independent risk factors leading to cardiovascular disease (CVD). These nutritional markers provide a thorough assessment of cardiovascular health status, revealing the biochemical environment associated with inflammation, lipid deposits, endothelial dysfunction, and clotting factors underlying cardiovascular disease. Using NMR fractionation technology for state-of-the-art lipid markers and independent risk factors, this nutritional test illuminates the complexity of cardiovascular disease (CVD).

Nearly 50% of all heart attack victims have normal levels of typical markers for CVD, including total cholesterol. For this reason, improved clinical tools are needed to identify patients with a predisposition to CVD who can benefit from timely, preventative intervention. With its unique combination of standard lipid markers, lipid fractionation analysis, and novel independent risk factors, we offer a test that helps patients identifying nearly 85% of individuals at risk for cardiovascular disease, allowing us to begin a treatment plan far in advance of a problem occurring.


What are advanced markers for Cardiovascular Disease?
  • LDL-Particle Number (LDL-P) includes small and large LDL particles, and is independent of the cholesterol concentration within the particles.  And individual with low/normal LDL-C concentration, but high LDL-P, is still at high-risk for plaque build-up.  Increased LDL-P is associated with increased risk of carotid atherosclerosis, angina, myocardial infarction, and future coronary events.
  • HDL-Particle Number (HDL-P) indicates increased risk of coronary events for individuals with a low HDL-P number, and is independent of major lipid and non-lipid CVD risk factors.  HDL-P is an important secondary risk factor, as it strongly relates to atherosclerosis in those individuals with optimal levels of LDL-P.  Increasing HDL-C without increasing HDL-P offers little clinical benefit.
  • LDL-Size is highly associated with triglycerides and insulin resistance.  Individuals with a preponderance of LDL particles of smaller size are at increased risk for coronary artery disease (CAD) and increased CAD severity.
  • Lipoprotein(a) or LP(a) is influenced by heredity and has a strong association with coronary and peripheral cardiac events.
  • hs C-reactive protein (hs-CRP) is an independent marker for systemic inflammation. High levels are linked to coagulation and vascular endothelium damage.
  • Lipoprotein-associated phospholipase (Lp-PLA2), aka PLAC, is produced in the intima, promoting inflammation and plaque instability. It is specific for vascular inflammation.
  • Homocysteine is an amino acid that has been linked to damaged endothelium, increased platelet aggregation, and the formation of atherosclerotic lesions.
  • Fibrinogen plays a key role in arterial occlusion by promoting thrombus formation, endothelial injury, and hyper-viscosity.
  • Insulin Resistance Score is determined by lipid sub-fractionation.
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